The Muscle + Brawn editorial team curates a science-driven guide to anti-aging supplements. It details how ubiquinol, omega-3s, collagen peptides, and antioxidants like vitamins D, C, and E support mitochondrial function, skin elasticity, metabolic health, and cognitive performance with human-trial-backed dosing recommendations.

Key points

• Ubiquinol enhances mitochondrial bioenergetics and reduces oxidative stress in aging cells.
• Omega-3 PUFAs mitigate inflammation, support cardiovascular integrity, and promote cognitive function.
• Collagen peptides with vitamin C cofactor drive skin elasticity improvements and joint matrix remodeling.

A multidisciplinary team at Louisiana State University develops an ensemble AI model by combining U-Net and DeepLabv3+ neural networks trained on 14 years of ROMS hindcast data. The approach integrates riverine nutrient loads and two-day hydrodynamic forecasts to predict daily hypoxic extents on the Louisiana–Texas shelf, supporting real-time nutrient reduction scenario testing.

Key points

• Ensemble uses U-Net and DeepLabv3+ CNNs for pixel-wise binary classification of bottom hypoxia.
• Inputs include potential energy anomaly (PEA), reconstructed sediment oxygen consumption (SOCrec), and temperature-dependent decomposition rate (DCPTemp).
• Trained on 14-year ROMS-NEMURO hindcast, model achieves median accuracy 0.85 and F1 score 0.72 for daily hypoxia forecasts.

Why it matters: This hybrid AI approach transforms coastal hypoxia forecasting by integrating physics-based and machine learning models to empower managers with timely water quality predictions.

The Columbia University team demonstrates that taurine supplementation in middle-aged mice extends median lifespan by up to 12% and enhances health span through improved bone mass, muscle endurance, and immune function. Comparable benefits in rhesus monkeys and human correlations support taurine’s potential as an affordable anti-aging intervention.

Key points

• Taurine levels decline substantially with age in mice, rhesus macaques, and humans, driving aging.
• Daily taurine supplementation in middle-aged mice increases median lifespan by 10–12% and improves bone mass, muscle endurance, and immune function.
• Taurine restores mitochondrial function, reduces DNA damage, and suppresses cellular senescence, linking to improved health span.

Why it matters: This finding highlights taurine supplementation as a low-cost dietary strategy to extend lifespan and health span, offering a promising anti-aging approach.

The NASA research group develops a targeted mitochondrial replacement therapy that transplants undamaged mitochondria isolated preflight into human cells. By supplementing damaged organelles, the approach restores cellular energetics after radiation exposure and counteracts age-related mitochondrial dysfunction, potentially extending healthy lifespan and mitigating cardiovascular and neurodegenerative diseases.

Key points

• NASA’s STMD-funded project harvests autologous healthy mitochondria and transplants them to counteract radiation and aging damage.
• Extracellular vesicles deliver mitochondria to restore ATP production and reduce oxidative stress in human cell models.
• In vitro studies inform dosage, timing, and system design for deep space missions and broader anti-aging applications.

Why it matters: This therapy offers a novel avenue to prevent radiation-induced damage and treat age-related diseases by replenishing mitochondrial function globally.