A 2025 study revealed that targeting ADAM19, a protein linked to cellular aging, significantly cuts down senescence markers and inflammation. Researchers from the Buck Institute and Lifespan Research Institute used flies, mice, and human cells to demonstrate reduced gut permeability when ADAM19 activity was blocked. This finding opens the door for innovative strategies in longevity research.

Q&A

  • What is the role of ADAM19 in cellular senescence?
  • How did the study evaluate gut permeability?
  • Can these findings be translated to human treatments?
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