Time.news' feature interview with Dr. Vivian Holloway presents evidence-based interventions—ranging from early-life habit formation and regular strength training to nighttime fasting and cognitive challenges—that collectively contribute to enhanced healthspan and functional resilience. By emphasizing a multi-dimensional approach to inflammation control, metabolic health, and muscle preservation, this holistic framework underscores practical, scientifically grounded strategies for mitigating age-related decline.

Key points

  • Time-restricted feeding protocols activate autophagy pathways and improve insulin sensitivity via extended nightly fasting windows.
  • Resistance training preserves muscle fiber integrity and counteracts sarcopenia by stimulating mTOR-mediated protein synthesis.
  • Neurocognitive stimulation supports synaptic plasticity and memory retention, mitigating age-related decline in executive functions.

Why it matters: This integrated lifestyle framework offers accessible, evidence-backed methods to prevent age-related decline, potentially reshaping public health and geroprotection.

Q&A

  • What is healthspan and how does it differ from lifespan?
  • How does time-restricted feeding promote longevity?
  • Why is strength training crucial for healthy aging?
  • What role does inflammation play in the aging process?
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Anti-Aging: Eat Less, Fast Longer