MD/Process presents MitoThrive™, a comprehensive NAD+ booster combining Nicotinamide Riboside, CoQ10, PQQ, resveratrol, and adaptogens. It enhances mitochondrial function and sirtuin activity to support energy production, cognitive clarity, and healthy aging.
Key points
Nicotinamide Riboside precursor elevates NAD+ pools to boost mitochondrial ATP synthesis.
PQQ and CoQ10 synergize to promote mitochondrial biogenesis and enhance energy output.
Trans-Resveratrol with adaptogens supports sirtuin activation, antioxidant defense, and stress resilience.
Why it matters:
By addressing NAD+ decline through a synergistic, multi-precursor formula, MitoThrive™ represents a shift toward root-cause cellular therapies for sustained energy, cognitive resilience, and healthy aging.
Q&A
What is NAD+ and why is it crucial?
How does Nicotinamide Riboside elevate NAD+ levels?
What role does PQQ play in mitochondrial health?
Are there any interactions or side effects to consider?
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Academy
Nicotinamide Adenine Dinucleotide (NAD+): A Key Molecule in Longevity Science
Nicotinamide Adenine Dinucleotide, or NAD+, is a coenzyme found in every cell of the human body. It acts as an electron carrier in redox reactions, essential for converting the food we eat into the energy our cells use. Beyond its role in metabolism, NAD+ plays vital roles in DNA repair, gene expression, and cell survival.
Why NAD+ Matters for Aging
As we age, NAD+ levels naturally decline—by over 50% from early adulthood to old age. This drop is linked to common signs of aging such as low energy, cognitive decline, slower metabolism, and reduced stress resilience. Research suggests that maintaining healthy NAD+ levels can:
- Promote mitochondrial health to sustain energy production.
- Activate sirtuins, proteins that regulate DNA repair and inflammation.
- Enhance cellular resilience against oxidative stress.
- Support healthy metabolic balance and brain function.
Natural and Supplemental Precursors
The body cannot absorb NAD+ directly from food or supplements. Instead, it relies on precursor molecules that it can convert into NAD+. The most studied NAD+ precursors include:
- Nicotinamide Riboside (NR): A form of vitamin B3 with high bioavailability and clinical support for raising NAD+ levels.
- Nicotinamide Mononucleotide (NMN): A direct downstream precursor to NAD+ that has shown promise in animal and early human studies.
- Nicotinamide (NAM): A common form of vitamin B3, though it may require larger doses and conversion steps.
Emerging Supplement Strategies
Modern NAD+ boosters often combine multiple cofactors to support different aspects of cellular health:
- PQQ (Pyrroloquinoline Quinone): Stimulates mitochondrial biogenesis, increasing both the number and function of mitochondria.
- CoQ10: Essential for the electron transport chain and heart health, bolstering overall energy metabolism.
- Polyphenols: Antioxidants like resveratrol help protect cells and enhance sirtuin activity.
- Adaptogens: Botanicals such as Rhodiola Rosea and L-Theanine help the body manage stress and support mental focus.
Healthy Lifestyle Complements
For optimal benefits, NAD+ support is best combined with:
- Balanced Nutrition: Diets rich in vitamins, minerals, and polyphenols support cellular repair.
- Regular Exercise: Physical activity boosts mitochondrial function and NAD+ recycling.
- Quality Sleep: Restorative sleep aids NAD+ restoration and DNA repair processes.
- Stress Management: Mindfulness and relaxation techniques reduce NAD+ depletion from chronic stress.
Understanding and supporting NAD+ metabolism is at the forefront of longevity science. By addressing this fundamental coenzyme, we can aim for sustained energy, cognitive clarity, and long-term health.
