In a comprehensive study published by Nature Communications, researchers led by Tiepeng Liao used integrative single-cell metabolomics to profile oxidative stress and senescence. Their work identifies distinct metabolite signatures—MROR and MROS—that forecast cellular aging. This approach offers promising avenues for longevity research through advanced metabolomic profiling.

Q&A

  • What is single-cell metabolomics?
  • What does cellular oxidation imply?
  • What are MROR and MROS cells?
  • What is pseudotime analysis?
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Integrative single-cell metabolomics and phenotypic profiling reveals metabolic heterogeneity of cellular oxidation and senescence