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Khaled Alqahtani and Arwa Sultan Alqahtani published a 2025 study in Scientific Reports, detailing how ML models like ADA-KNN and SBNNR refine PLGA nanoparticle synthesis for drug delivery. Their method uses techniques like LOF and bat optimization, offering actionable insights for optimizing nanoparticle parameters.

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Utilization of machine learning approach for production of optimized PLGA nanoparticles for drug delivery applications