A cross-sectional NHANES study led by Nantong University and Shanghai Lida University shows anti-inflammatory diets significantly reduce phenotypic age acceleration and mitigate adverse effects of vigorous-intensity exercise on biological aging.
Key points
- Anti-inflammatory diets reduce phenotypic age acceleration by up to 2.72 years compared to pro-inflammatory diets.
- Sufficient vigorous physical activity alone increases PhenoAgeAccel by 0.81 years, but its pro-aging effects are offset when combined with an anti-inflammatory diet.
- CatBoost machine-learning analysis identifies BMI, DII, gender, age, race, and physical activity as top predictors of biological aging.
Why it matters: Demonstrates how targeted dietary inflammation control can modulate biological aging and improve longevity outcomes.
Q&A
- What is phenotypic age acceleration?
- How is the Dietary Inflammatory Index (DII) measured?
- Why can vigorous physical activity accelerate aging?
- How does diet offset the aging effects of intense exercise?