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May 10 in Longevity and AI

Gathered globally: 12, selected: 10.

The News Aggregator is an artificial intelligence system that gathers and filters global news on longevity and artificial intelligence, and provides tailored multilingual content of varying sophistication to help users understand what's happening in the world of longevity and AI.


Researchers at KU Leuven deploy an AI-augmented wearable system combining behind-the-ear EEG and accelerometry to automate sleep staging and extract physiological features. They train a multilayer perceptron to discriminate Alzheimer’s patients from healthy elderly, achieving AUC 0.90 overall and 0.76 for prodromal cases, demonstrating promise for scalable, noninvasive Alzheimer’s screening.

Key points

  • SeqSleepNet AI achieves five-class sleep staging on two-channel wearable EEG and accelerometry, reaching 65.5% accuracy and Cohen’s kappa 0.498.
  • An elastic-net-trained MLP extracts spectral features (e.g., 9–11 Hz in wake, slow activity in REM) to classify Alzheimer’s vs. controls with AUC 0.90 overall and 0.76 for prodromal cases.
  • Physiological sleep biomarkers from spectral aggregation outperform hypnogram metrics, enabling scalable home-based Alzheimer’s screening via a single-channel wearable.

Why it matters: Integrating wearable EEG and AI-driven sleep analysis shifts Alzheimer’s screening toward accessible, noninvasive remote diagnostics with high accuracy.

Q&A

  • What is SeqSleepNet?
  • What are physiological features in this study?
  • Why is single-channel EEG sufficient for screening?
  • What does AUC mean and why is it important?
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Wearable sleep recording augmented by artificial intelligence for Alzheimer's disease screening

A team at the University of Barcelona employs adeno-associated virus serotype 9 to deliver the Klotho gene in adult mice. The single-dose treatment elevates s-KL protein levels systemically and in the brain, yielding nearly 20% longer lifespans alongside preserved muscle function, bone volume and cognitive resilience. Their findings illustrate a multi-organ anti-aging approach targeting fundamental longevity processes rather than individual diseases.

Key points

  • AAV9-mediated delivery of s-KL via intravenous and intracerebroventricular injections in mice
  • 19.7% lifespan extension with preserved muscle, bone and cognitive functions
  • Enhanced muscle regeneration, improved trabecular bone architecture and increased hippocampal neurogenesis

Why it matters: Targeting Klotho offers a unified, multi-tissue anti-aging approach that could transform longevity medicine beyond single-disease treatments.

Q&A

  • What is Klotho protein?
  • How does AAV9 delivery work in gene therapy?
  • Why use both intravenous and intracerebral injections?
  • What are potential risks of Klotho gene therapy?
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Researchers from the Electronics Research Institute and Badr University present a FR4-based dual-band microwave bandpass filter sensor employing split-ring resonators for noninvasive blood glucose measurement. By tracking S-parameter shifts at 2.45 and 5.2 GHz and applying CatBoost and Random Forest models, the system correlates dielectric changes in tissue with glucose concentrations, offering a compact, low-cost alternative to invasive glucose monitoring.

Key points

  • FR4-based dual-band bandpass filter sensor with concentric split-ring resonators tuned at 2.45 GHz and 5.2 GHz for glucose sensing.
  • S-parameter (S11 and S21) shifts in resonant frequency, magnitude, and phase track glucose-dependent permittivity changes.
  • Integration with nanoVNA measurements and Random Forest/CatBoost classifiers achieves sensitivity up to 2.026 MHz/(mg/dL) and 0.011 dB/(mg/dL).

Why it matters: This dual-band microwave sensor with AI analysis could revolutionize diabetes care by offering highly sensitive, noninvasive glucose monitoring without needles.

Q&A

  • How do split-ring resonators detect glucose?
  • What role does machine learning play?
  • How does the finger phantom model work?
  • Is microwave exposure safe for monitoring?
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Noninvasive blood glucose monitoring using a dual band microwave sensor with machine learning

Alan Tomusiak reviews animal and human studies to demonstrate that methods like senescent cell clearance boost healthspan without notably extending maximum lifespan, whereas caloric restriction significantly slows aging. He contrasts PhenoAge and GrimAge epigenetic clocks and genetic variants to highlight distinct pathways controlling healthspan versus lifespan.

Key points

  • Senescent cell clearance improves healthspan but leaves maximum lifespan largely unchanged in mice.
  • Caloric restriction significantly delays both disease onset and maximum lifespan limits via metabolic stress pathways.
  • Epigenetic clocks PhenoAge and GrimAge capture different aging dimensions, highlighting divergence of healthspan and mortality predictions.

Why it matters: Understanding separate aging endpoints guides development of targeted therapies that optimize both disease resistance and lifespan extension.

Q&A

  • What distinguishes healthspan from maximum lifespan?
  • How do senescent cells affect aging?
  • Why does caloric restriction extend maximum lifespan?
  • What are PhenoAge and GrimAge clocks?
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Maximum Lifespan vs. Healthspan (Alan Tomusiak)

Led by Tom Cruise’s longtime trainer, a nine-step regimen emphasizes dynamic stretching, strategic HIIT, precise hydration, anti-inflammatory nutrition, quality sleep, strength training, mindfulness, and cold exposure. Each practice targets cellular aging pathways—boosting synovial fluid, growth hormone, mitochondrial function, autophagy, and stress resilience—to support sustained vitality and slow biological aging across all fitness levels.

Key points

  • Dynamic stretching increases synovial fluid production and restores joint range of motion.
  • 20-minute HIIT sessions elevate growth hormone by over 500%, enhancing muscle preservation and metabolic health.
  • Cold exposure induces heat-shock proteins and activates brown adipose tissue, improving cellular repair and energy metabolism.

Why it matters: By integrating simple, science-backed daily practices, this regimen offers a scalable strategy to delay aging and enhance long-term healthspan.

Q&A

  • What is synovial fluid?
  • How does HIIT increase growth hormone?
  • What is hormesis in cold exposure?
  • How does time-restricted eating support autophagy?
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A joint effort by NooCube’s R&D group and researchers at Harvard Medical School introduces a pharmaceutical-grade NMN formula paired with resveratrol and hydroxytyrosol. This blend elevates NAD+ bioavailability to support mitochondrial energy output, DNA repair pathways, and metabolic resilience for anti-aging benefits.

Key points

  • Pharmaceutical-grade NMN (250 mg) paired with resveratrol, hydroxytyrosol, and niacinamide to optimize NAD+ biosynthesis.
  • Synergistic activation of sirtuin and PARP DNA repair pathways enhances mitochondrial efficiency and cellular stress resilience.
  • Clinical pilot data indicate over 20% increase in blood NAD+ levels and improved energy, cognitive clarity, and metabolic markers.

Why it matters: This optimized NMN formulation shifts anti-aging strategies toward targeted NAD+ restoration, offering superior bioavailability and synergistic antioxidant support over conventional precursors.

Q&A

  • What is NMN?
  • How does NMN boost cellular energy?
  • Why combine NMN with resveratrol?
  • Are there side effects of NMN supplements?
  • How do I choose a high-quality NMN supplement?
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Best NMN Supplements 2025 : Top NMN and NR Supplement Boosters for Anti - Aging and Energy From NooCube NAD+

Katie Fry and the Revive Rejoice health editors present ten scientifically supported anti-aging foods, from extra virgin olive oil to pomegranates, explaining how their key nutrients and antioxidants combat oxidative stress and support collagen, brain, and cardiovascular health.

Key points

  • Extra virgin olive oil supplies 73% MUFAs and phenolic antioxidants to reduce inflammation and oxidative stress.
  • Green tea EGCG and polyphenols neutralize free radicals, protect brain cells, and support UV defense.
  • Omega-3 fatty acids from fatty fish and flaxseed maintain cell membranes, reduce inflammation, and stimulate collagen synthesis.

Why it matters: Highlighting evidence-based dietary choices empowers individuals to leverage natural compounds for slowing cellular aging and reducing chronic disease risk.

Q&A

  • What are free radicals and antioxidants?
  • How do monounsaturated fats support skin health?
  • Why is EGCG in green tea important for aging?
  • What makes lycopene more bioavailable with fat?
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MarketsandMarkets publishes an analysis forecasting the AI in healthcare market’s expansion from US$14.92 billion in 2024 to an estimated US$110.61 billion by 2030. The report examines growth drivers such as chronic disease detection via imaging analytics, demographic shifts, and strategic regional investments, segmented by technology, end user, and geography.

Key points

  • Deep learning holds the largest segment share by processing unstructured medical data for diagnostics and predictive analytics.
  • Asia Pacific leads regional growth due to aging demographics, government investment, and telemedicine expansion.
  • Major industry players like Philips, Microsoft, and NVIDIA drive market through partnerships, R&D, and cloud-based AI platforms.

Q&A

  • What drives the high CAGR in AI healthcare?
  • Why does deep learning dominate AI healthcare?
  • How does the Asia Pacific region contribute to market growth?
  • What role do strategic partnerships play?
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Research and Markets presents its ‘Artificial Intelligence in Military Market Opportunities and Strategies to 2034’ report, assessing regional market sizes and growth drivers using CAGR analysis. The study evaluates hardware, software, and services segments, identifies leading competitors and strategic trends, and forecasts market expansion through 2034 to inform defense planning and AI adoption strategies.

Key points

  • Global military AI market grows from $9.67 B in 2024 to $23.97 B in 2029 at 19.91% CAGR, reaching $61.08 B by 2034.
  • Software leads with a 42.73% share in 2024, while hardware is the fastest-growing segment at a 24.25% CAGR through 2029.
  • Asia Pacific and Middle East top regional growth with CAGRs of 23.78% and 22.23%, respectively.

Why it matters: Understanding military AI market dynamics enables defense planners to optimize investments, accelerate technology adoption, and maintain strategic superiority in evolving geopolitical landscapes.

Q&A

  • What is CAGR and why is it important in market forecasting?
  • What does context-aware computing mean in military AI?
  • How do new procurement and upgradation segments differ?
  • What are EO/IR intelligent sensing systems in defense?
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$61.08 Bn Artificial Intelligence in Military Market

DataM Intelligence forecasts the AI chip market expanding from US$25.12 billion in 2022 to US$335.02 billion by 2031 (CAGR 38.41%), powered by GPUs, ASICs and FPGAs used in cloud, edge and embedded AI applications.

Key points

  • Report forecasts AI chip market growth from US$25.12 billion (2022) to US$335.02 billion (2031) at 38.41% CAGR.
  • Segments include GPU, ASIC, FPGA, CPU types; cloud vs. edge processing; and packaging tech like SoC, SiP, MCM.
  • Leading players: Intel, AMD, NVIDIA, Google, Samsung, Qualcomm and challengers such as Tenstorrent.

Why it matters: A nearly 13-fold market expansion underscores AI hardware’s pivotal role in powering next-generation intelligent services, smart devices and high-performance research applications.

Q&A

  • What is an AI chip?
  • Why is the market CAGR so high?
  • How do U.S. tariffs affect the AI chip market?
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Artificial Intelligence (AI) Chip Market is expected to reach US$ 335.02 billion by 2031 | MediaTek Inc, Google, Samsung Electronics Co Ltd, Qualcomm Technologies Inc, Alphabet Inc