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May 9 in Longevity and AI

Gathered globally: 19, selected: 15.

The News Aggregator is an artificial intelligence system that gathers and filters global news on longevity and artificial intelligence, and provides tailored multilingual content of varying sophistication to help users understand what's happening in the world of longevity and AI.


A team led by Michael Levin at Tufts University’s Allen Discovery Center reveals that bioelectric voltage gradients across non-neuronal cells act as programmable “software” atop genetic “hardware.” By modulating ion channel and gap junction activity, they induce amphibian limb regeneration, cancer suppression, and novel organism constructs, offering new avenues for tissue engineering and longevity.

Key points

  • Targeted ion channel drugs alter membrane voltage in planarian and frog models, inducing multi-headed regeneration without genetic changes.
  • Maintaining electric connectivity in tumor-bearing amphibian cells suppresses oncogenic growth despite persistent oncoprotein expression.
  • Programming bioelectric circuits in frog embryonic and human tracheal epithelial cells yields self-motile xenobots and anthrobots with self-replication and wound-healing capabilities.

Why it matters: Bioelectric pattern modulation represents a paradigm shift, offering a reversible, non-genetic approach to direct tissue regeneration, cancer suppression, and anti-aging therapies.

Q&A

  • What is bioelectricity?
  • How do ion channels influence tissue patterning?
  • What are xenobots and anthrobots?
  • How can bioelectricity be used to suppress cancer?
  • Why is bioelectricity important in aging?
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A team at Thomas Jefferson University uses a mouse model lacking SIRT6 in spinal disc cells to show that SIRT6 deficiency elevates histone acetylation, DNA damage, and cellular senescence, while impairing autophagy, thereby accelerating intervertebral disc degeneration.

Key points

  • Conditional deletion of Sirt6 in AcanCreERT2;Sirt6fl/fl mice accelerates lumbar and caudal disc degeneration.
  • Loss of SIRT6 elevates H3K9 acetylation, disrupts chromatin accessibility, and alters transcriptomic SASP signatures.
  • Sirt6 deficiency increases γH2AX DNA-damage foci, raises p21/p19 levels, and decreases LC3-mediated autophagy in disc cells.

Why it matters: Identifying SIRT6 as an epigenetic gatekeeper of disc health suggests new therapeutic strategies to combat age-related spinal degeneration.

Q&A

  • What is SIRT6?
  • Why target intervertebral discs?
  • How does SIRT6 loss impair autophagy?
  • What is SASP in this context?
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Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice

Whoop, the wearables manufacturer, releases the 5.0 tracker with extended battery life, tiered subscriptions, Healthspan biomarker scores, and on-demand ECG via its MG model, refining its platform to focus on longevity and holistic health insights.

Key points

  • Tiered subscriptions offer three levels—including Whoop One, Peak, and Life—unlocking features from basic sleep and strain metrics to medical-grade ECG and beta blood pressure insights.
  • Healthspan metric aggregates nine biomarkers—heart rate zones, sleep consistency, VO2 max, and lean body mass—to calculate physiological age and Pace of Aging.
  • Hardware upgrades deliver a 14-day battery life, new wireless PowerPack, and redesigned module with optical sensors for ECG and non-invasive blood pressure estimation.

Why it matters: This update positions Whoop at the forefront of longevity-focused wearables by combining extended battery life with actionable biomarker analytics previously limited to clinical settings.

Q&A

  • What is the Healthspan metric?
  • How reliable is Whoop’s heart rate monitoring?
  • What does the subscription model include?
  • How does ECG on the MG model work?
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Whoop 5 . 0 review : A bold leap into longevity with familiar drawbacks

A team at Bar-Ilan University’s Sagol Center maps acetylation sites across 107 mammalian species and uses computational analyses to link specific protein modifications with extended lifespan, suggesting targeted acetylation mimics could counter age-related damage.

Key points

  • Comparative acetylome profiling across 107 mammals identifies ~300 lifespan-linked acetylation sites.
  • PHARAOH computational analysis correlates specific acetyl modifications with DNA repair, metabolism, and stress pathways.
  • Experimental mice models with humanized acetylation sites to assess effects on lifespan and healthspan.

Why it matters: Decoding evolutionary acetylation patterns reveals tunable mechanisms for lifespan extension, paving the way for novel anti-aging therapies.

Q&A

  • What is protein acetylation?
  • How does the PHARAOH tool work?
  • Why compare different mammals?
  • What are potential therapies targeting acetylation?
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The Global Wellness Institute debuts The Wellness Roundtable podcast, featuring practitioners and experts discussing applied longevity science—from AI diagnostics to regenerative therapies—in digestible under-hour episodes tailored to clinical, coaching, and entrepreneurial audiences.

Key points

  • Podcast hosted by Global Wellness Institute features under-hour expert discussions on applied longevity science
  • Episodes cover AI-powered diagnostics, epigenetic aging clocks, and regenerative medicine approaches
  • Target audience includes clinicians, coaches, and entrepreneurs to drive real-world healthspan applications

Why it matters: This podcast uniquely equips front-line wellness professionals with actionable longevity science, accelerating the translation of emerging therapies into everyday practice.

Q&A

  • What is 'longevity washing'?
  • Who sponsors The Wellness Roundtable podcast?
  • Why focus on practitioners rather than consumers?
  • What are 'healthspan' diagnostics?
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Global Wellness Institute Launches New Podcast, The Wellness Roundtable: Longevity, On May 14

Dermatology experts adopt a skin longevity paradigm, measuring biological age with telomere and NAD+ assays and recommending tailored supplement and pro-aging routines to maintain skin function and appearance.

Key points

  • Telomere length and NAD+ assays quantify biological skin age
  • Personalized pro-aging supplement programs support cellular resilience
  • Regenerative modalities like exosomes and polynucleotides enhance dermal repair

Why it matters: Prioritizing skin longevity over anti-aging signals a paradigm shift toward functional health and proactive interventions, improving both appearance and systemic well-being.

Q&A

  • What is biological age?
  • How does telomere length testing work?
  • What role does NAD+ play in skin aging?
  • What are regenerative aesthetic treatments?
  • How does pro-aging differ from anti-aging?
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Leading Edge Health’s GenuinePurity introduces Longevity+, a cellular repair supplement delivering clinically studied doses of NMN, Cycloastragenol, CoQ10, Resveratrol and Selenium via enteric-coated capsules to enhance NAD+ levels, telomere maintenance and mitochondrial function for healthier aging.

Key points

  • Delivers clinically validated doses of NMN, Cycloastragenol, CoQ10, Resveratrol and Selenium in each capsule.
  • Uses pharmaceutical-grade enteric coating to protect ingredients from stomach acid and enhance intestinal absorption.
  • Supports multi-pathway longevity by boosting NAD+ levels, activating telomerase and optimizing mitochondrial bioenergetics.

Why it matters: By combining five clinically studied longevity compounds in an enteric-coated delivery, Longevity+ addresses absorption and multi-pathway repair, setting a new standard for single-capsule anti-aging therapy.

Q&A

  • What is NMN and why boost it?
  • How does enteric coating improve absorption?
  • What role does Cycloastragenol play?
  • Is Longevity+ safe for long-term use?
  • Why combine five nutrients in one pill?
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Best Cellular Repair Supplement with Lifespan-Extending Nutrients for Longevity & Healthy Cell Function

A team at Peking Union Medical College Hospital applies machine learning to integrate quantitative MRI radiomic features and clinical variables, building a Random Forest classifier that predicts bevacizumab response in metastatic brain tumor–induced peritumoral edema with 0.91 AUC.

Key points

  • Integrated 13 radiomic and eight clinical features from 300 metastatic brain tumor patients.
  • Applied stratified 70/30 train-test split, SMOTE oversampling, and tenfold cross-validation across RF, LR, GBT, and NB.
  • Random Forest achieved 0.89 accuracy, 0.91 AUC-ROC, and identified edema volume as the most important predictor.

Why it matters: Precision prediction of bevacizumab response can reduce unnecessary risks and costs, improving edema management in neuro-oncology.

Q&A

  • What is bevacizumab?
  • How does radiomics differ from standard imaging?
  • What is Random Forest in machine learning?
  • Why use SMOTE for class imbalance?
  • What does AUC-ROC measure?
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Predicting the Efficacy of Bevacizumab on Peritumoral Edema Using Machine Learning

Research and Markets presents a comprehensive analysis of AI-driven drug discovery, detailing how machine learning, deep learning, and NLP optimize target identification and repurposing, projecting the market’s rise from $1.72B to $8.53B by 2030 across global regions.

Key points

  • Market valued at $1.72B in 2024 and projected to reach $8.53B by 2030 with a 30.59% CAGR
  • Integration of machine learning, deep learning, and NLP accelerates target identification, protein prediction, and drug repurposing
  • North America leads with 43% share, while Europe and APAC grow through supportive regulations and national AI strategies

Why it matters: AI-driven drug discovery offers unprecedented speed and cost efficiency, reshaping pharmaceutical R&D and accelerating therapeutic development.

Q&A

  • How does AI improve drug target identification?
  • What is the role of AlphaFold in drug discovery?
  • Why is the North American market leading in AI drug discovery?
  • What challenges hinder AI adoption in drug discovery?
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Artificial Intelligence in Drug Discovery Market Outlook

An Osaka University team maps fMRI signals to visual and semantic features, then leverages a Stable Diffusion model to synthesize high-fidelity reconstructions of perceived and imagined scenes, improving data efficiency and broadening brain–computer interface applications.

Key points

  • Parallel fMRI decoders predict latent image features and semantic embeddings to condition diffusion-based reconstructions.
  • Stable Diffusion generates high-fidelity images from neural predictors with minimal subject-specific training data.
  • Two-stage pipelines capture both low-level visual layouts and high-level semantics for static and dynamic brain decoding.

Why it matters: This advance demonstrates practical brain-to-image decoding with high fidelity, opening avenues for noninvasive communication via visual brain–computer interfaces.

Q&A

  • How do diffusion models differ from GANs in brain decoding?
  • What role do semantic embeddings play in image reconstruction?
  • Why do models need subject-specific training?
  • What limits the resolution of fMRI-based reconstructions?
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AI and the Reconstruction of Dreams and Visual Experiences from Brain Scans

MarketBeat’s proprietary stock screener tool selects seven AI-focused equities—Super Micro Computer (SMCI), Salesforce (CRM), ServiceNow (NOW), Arista Networks (ANET), Accenture (ACN), QUALCOMM (QCOM), and Tempus AI (TEM)—by filtering for highest dollar trading volumes and key fundamental metrics, guiding intermediate investors toward sector momentum and potential returns.

Key points

  • Super Micro Computer (SMCI) traded 15.24 M shares mid-day, with P/E 16.37 and quick ratio 1.93.
  • Salesforce (CRM) saw 1.74 M volume at $273.78, with P/E 44.93, PEG 2.58, and current ratio 1.11.
  • Tempus AI (TEM) recorded 4.41 M volume at $53.15, debt/equity 8.17, and 50-day MA $47.95.

Q&A

  • What determines AI stock performance?
  • Why is trading volume important?
  • What is a PEG ratio?
  • How are quick and current ratios used?
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MarketBeat’s proprietary stock screener analyzed recent dollar trading volumes to rank the five most actively traded AI-focused companies. This analysis spotlights Qualcomm’s semiconductor innovations, ServiceNow’s intelligent workflow platform, Super Micro’s high-performance server hardware, Salesforce’s CRM AI integrations, and Monolithic Power Systems’ power electronics solutions—providing a comprehensive view of leading AI investments.

Key points

  • MarketBeat's volume-based screener identifies the top five AI stocks by recent dollar trading volume.
  • Detailed metrics include trading volume, moving averages, market cap, P/E and PEG ratios, and stock beta.
  • Selected companies span chip design, intelligent workflow platforms, AI-optimized servers, CRM integrations, and power electronics for data centers.

Q&A

  • What defines an AI stock?
  • How does MarketBeat’s screener rank AI stocks?
  • What is the significance of P/E and PEG ratios for AI stocks?
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The Vector Institute, an independent non-profit, awards 120 merit-based $17,500 scholarships to top AI master’s students in Ontario across engineering, computer science, health informatics, and business analytics. Since 2018, VSAI has supported over 800 scholars and facilitated hiring of more than 2,500 Vector-affiliated graduates, reinforcing Ontario’s position as a global AI research and innovation hub.

Key points

  • 120 merit-based $17,500 scholarships awarded totaling $2.1 million for the 2025-26 academic year.
  • Recipients represent 15 Ontario universities across engineering, computer science, health informatics, and business analytics.
  • VSAI links scholars to Vector’s Digital Talent Hub and industry partnerships, supporting placement of over 2,500 Vector-affiliated graduates.

Why it matters: The Vector Scholarship in AI cultivates Ontario’s AI talent pipeline by funding graduate research, fostering industry-academia collaboration, and accelerating innovation across sectors.

Q&A

  • What is the Vector Scholarship in Artificial Intelligence?
  • Who is eligible for VSAI?
  • How are recipients selected?
  • What benefits do scholars receive beyond funding?
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Vector Institute awards up to $2.1 million in scholarships

Vamsi Krishna Reddy Munnangi at TechBullion examines AI-driven machine learning models that analyze API traffic, predict demand, and implement adaptive caching. The approach enhances performance by reducing latency, fortifies security through anomaly detection, and introduces predictive maintenance to anticipate failures, ensuring resilient, self-healing cloud-native API infrastructures for modern distributed systems.

Key points

  • Machine learning algorithms analyze API traffic patterns and dynamically allocate resources, cutting response latency by up to 25%.
  • AI-driven anomaly detection monitors millions of API events per second, identifying security threats and reducing incident detection time by over 50%.
  • Predictive maintenance models forecast API failures and enable self-healing by auto-restarting services and rerouting traffic, reducing unplanned downtime by up to 70%.

Why it matters: By automating performance optimization, security monitoring, and maintenance, this AI-driven model transforms API operations with unprecedented efficiency and resilience.

Q&A

  • What are cloud-native APIs?
  • How does AI predict API traffic spikes?
  • What is adaptive caching in API management?
  • How do self-healing systems work in cloud-native environments?
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Revolutionizing Cloud-Native API Management with Artificial Intelligence

In a key decision, the Federal Circuit holds that patents claiming generic machine learning methods applied to existing problems lack eligibility under Section 101, reinforcing that AI inventions must involve genuine technical improvements to secure patent protection.

Key points

  • Federal Circuit affirms Section 101 dismissal of ML patent claims applying generic algorithms to scheduling and mapping use cases.
  • Court finds no improvement to core machine learning models or training techniques, deeming them “conventional” and ineligible.
  • Decision underscores that automating known human tasks with standard ML methods without technical innovation fails patent eligibility.

Why it matters: This ruling establishes a stricter patentability threshold for AI inventions, emphasizing substantive technical contributions over mere applications of off-the-shelf machine learning techniques.

Q&A

  • What is Section 101 in patent law?
  • Why are generic machine learning methods ineligible under Section 101?
  • How will this decision affect future AI patent filings?
  • What qualifies as a technical improvement in ML patents?
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Federal Circuit Clarifies Limits of Patent Eligibility for Machine Learning Claims | Fish & Richardson