Montana’s legislature has legalized so-called “experimental treatment centers,” allowing clinics to administer FDA-unapproved therapies—ranging from peptide and gene injections to NAD+ infusions—for longevity outside the typical trial framework.

Key points

• Montana law licenses clinics to administer Phase 1-only anti-aging therapies without FDA Phase 2/3 approval.
• Therapies include NAD+ infusions, peptide/gene protocols targeting follistatin and klotho proteins.
• Clinics must allocate 2% of profits to low-income patients, expanding access beyond terminally ill groups.

Why it matters: By cutting regulatory delays, this law could accelerate human testing of novel longevity modalities, but raises critical safety and equity considerations.

Dr. Ian Pearson, Ray Kurzweil and Aubrey de Grey forecast routes to human immortality: Pearson envisions mind uploading and 3D-printed organs; Kurzweil predicts AI-human brain integration via Neuralink-style interfaces; de Grey proposes integrative rejuvenation therapies targeting cellular damage. Together they outline technologies to halt aging and extend lifespans to 1,000 years.

Key points

• Dr. Ian Pearson predicts mind uploading and 3D-printed organs will enable digital immortality for the wealthy by 2050.
• Ray Kurzweil forecasts AI-human brain integration via Neuralink-style interfaces will spark the Singularity by 2029, leading to cyborg immortality by 2045.
• Aubrey de Grey’s integrative rejuvenation uses senolytics, gene therapies and cellular repair protocols to achieve longevity escape velocity and cure aging as a disease.

Why it matters: These projections herald a paradigm shift in aging research by framing longevity as a curable condition with transformative therapeutic potential.