Mark Garbinson of DGM News presents a curated list of evidence-backed supplements—such as curcumin, NMN, and astaxanthin—that target aging mechanisms by modulating sirtuins, enhancing mitochondrial function, and mitigating chronic inflammation to preserve skin elasticity, joint mobility, and cognitive performance.
Key points
- Trans-resveratrol acts as an antioxidant and activates sirtuin pathways to support cellular longevity.
- Ubiquinol-form CoQ10 enhances mitochondrial ATP production and reduces oxidative stress in cardiomyocytes.
- NMN and NR precursors elevate NAD+ levels to promote DNA repair and metabolic regulation.
Q&A
- What makes trans-resveratrol more bioavailable?
- How do sirtuins influence aging?
- Why combine curcumin with piperine?
- Are NAD+ precursors like NMN and NR interchangeable?
