Researchers at Breznikar analyze the global anti-aging beauty machine market, identifying demographic factors, disposable income, and technological innovations as primary drivers. They assess regulatory environments, distribution channels, pricing strategies, and geographic adoption patterns to inform industry stakeholders and advance accessible, effective skincare device solutions.

Key points

• UN projects over 2.1 billion people aged 60+ by 2050, boosting device demand globally.
• Advanced modalities—including LED therapy, radiofrequency, and ultrasound—deliver professional-grade skin rejuvenation with minimal downtime.
• E-commerce sales rose 25% (2020–2023) while clinics maintain 60% revenue share, expanding device accessibility across markets.

Why it matters: Understanding consumer, regulatory, and technological drivers in the anti-aging device market guides strategic decisions, accelerates innovation in longevity skincare solutions.

Researchers at the Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, and collaborators characterized serum FT4, T4, FT3, T3, TSH and FT3/FT4 ratios in 349 Chinese nonagenarians. They applied GAMLSS modeling and CLSI EP28 guidelines to derive age-specific reference intervals, revealing hormone shifts and links with BMI and WHtR to refine thyroid diagnostics in elderly care.

Key points

• Established nonparametric RIs for serum FT4 (10.39–20.46 pmol/L), T4 (81–193 nmol/L), FT3 (3.56–6.43 pmol/L), T3 (0.94–2.05 nmol/L), TSH (0.29–5.28 μIU/mL) and FT3/FT4 ratio (0.197–0.496) in 90+ Chinese cohort.
• Utilized GAMLSS centile curve modeling and CLSI EP28 guidelines to map hormone distributions and age-related shifts across 90–108 years.
• Identified significant positive correlation between FT4 and age, and associations of BMI/WHtR with FT3, T3 and FT3/FT4, integrating anthropometric factors in thyroid assessment.

Why it matters: Defining age-tailored thyroid hormone norms for nonagenarians ensures accurate diagnosis and management of thyroid disorders, reducing misdiagnosis and optimizing geriatric care.