A multidisciplinary team reviews four natural compounds—NMN, Fisetin, Astaxanthin, and Hydroxytyrosol—demonstrating their roles in longevity science. NMN elevates NAD+ to enhance metabolism and DNA repair; Fisetin targets senescent cells; Astaxanthin neutralizes oxidative stress; and Hydroxytyrosol supports cardiovascular function. Together, these interventions suggest a complementary strategy for mitigating age-related degeneration and extending healthspan.

Key points

• NMN elevates NAD+ levels by up to 40%, enhancing metabolic activity and DNA repair in mammalian cells.
• Fisetin acts as a senolytic, selectively inducing apoptosis in senescent “zombie” cells to reduce chronic inflammation.
• Astaxanthin delivers potent ROS scavenging—up to 6,000-fold stronger than vitamin C—improving cellular resilience.

Why it matters: These natural compounds offer a synergistic strategy to combat aging, potentially reshaping preventive medicine and improving healthspan without toxic side effects.

Neuralink’s research team has developed an AI-driven robotic platform that performs intricate neurosurgical procedures, notably brain-computer electrode insertion, with superior precision and reduced operating times. By integrating real-time analytics and robotic actuators, the system minimizes human error and enhances patient outcomes.

Key points

• AI-driven algorithms guide robotic arms for submicron electrode placement
• Micron-level positioning uses real-time kinematic feedback to ensure precision
• Real-time analytics adjust trajectories and minimize human variability
• Demonstrated 5× faster insertion times and 30% lower error rates versus manual
• Designed specifically for neurosurgical BCI electrode implantations

Why it matters: This advancement heralds a new era in surgical robotics, promising lower complication rates and broader access to high-precision procedures. By automating critical tasks, it could reduce surgeon fatigue and enable more consistent outcomes across diverse clinical settings.