NOVOS Labs presents four science-based biohacks—multi-ingredient supplementation, structured exercise, optimal hydration, and consistent sleep—designed to address key cellular aging mechanisms. By combining compounds that target inflammation and senescence with practices that promote autophagy, mitochondrial health, and glymphatic clearance, these strategies aim to improve biological age markers and extend healthspan.

Key points

• Calcium alpha-ketoglutarate extended lifespan and improved healthspan in aged mice by modulating inflammation and mitochondrial energy pathways.
• High-intensity interval and strength training stimulate autophagy, mitochondrial biogenesis, and myokine release, enhancing VO₂ₘₐₓ and reducing oxidative stress.
• Combined hydration protocols and a plant-forward, polyphenol-rich diet preserve cellular homeostasis, stabilize insulin signaling, and support gut microbiome diversity.

Why it matters: Integrating targeted biohacks with molecular and lifestyle approaches offers a scalable framework to slow biological aging and enhance long-term health.

Researchers at NOVOS Labs describe how a clinically tested blend of 12 ingredients—including glycine, AKG, fisetin, NMN, and magnesium—synergistically reduces oxidative stress, clears senescent cells, and boosts mitochondrial function to support men’s health span and strength.

Key points

• Formulation combines 12 clinically studied compounds including glycine, AKG, fisetin, NMN, and magnesium to target multiple aging pathways.
• Daily sachet delivery ensures consistent dosing to enhance mitochondrial function, glutathione synthesis, and senescent cell clearance.
• Evidence-based blend supports muscle health, inflammation reduction, and cellular repair in men, addressing sarcopenia and metabolic decline.

Why it matters: This guide presents a multi-modal, evidence-based supplement strategy that targets core cellular aging pathways more comprehensively than single-mechanism products.

Think of skin aging as a spring losing tension over time. Carnosine acts like an internal maintainer, neutralizing reactive molecules and blocking sugar from stiffening collagen fibers. Clinical studies highlight 500–1,000 mg daily under beta-alanine to sustain mitochondrial energy and cellular resilience. For example, adding carnosine to your supplement stack alongside NAD+ boosters can improve wrinkle appearance and muscle recovery, making it a strategic component in a comprehensive longevity regimen.

Key points

• Carnosine inhibits glycation and neutralizes free radicals to preserve skin collagen and cell health.
• Recommended dosage of 500–1,000 mg daily, ideally with beta-alanine, to boost antioxidant defense and mitochondrial function.
• Carnosine complements NAD+ boosters and supports skin repair, making it a strategic addition to longevity routines.

Just as scaffolding gives a building shape, collagen maintains youthful skin structure—but it needs lysine to tie its fibers together. Clinical data show that supplementing 1,500–2,000mg of lysine daily can improve collagen cross-linking and hydration, yielding firmer skin and reduced fine lines in 12 weeks. By pairing lysine-rich foods or supplements with NOVOS Core’s supportive ingredients, you can optimize skin repair and sustain elasticity as you age.

Key points

• Lysine enhances collagen cross-linking via lysyl oxidase for firmer skin.
• Recommended daily dosage ranges from 800mg to 3,000mg to support tissue repair and hydration.
• Combining lysine intake with NOVOS Core ingredients yields synergistic benefits for skin aging.