Just as a sturdy foundation keeps a building standing, robust immune resilience sustains your health into later years. Researchers at South Texas Veterans Health Care System found that strong immune resilience, driven by TCF7 activity, slashes mortality by 69% and improves vaccine responses. For example, mid-life TNFα-blockers might restore immune balance, delaying heart disease and Alzheimer’s.

Key points

• Boosting immune resilience between ages 40 and 70 links to a 69% lower mortality risk.
• TCF7 transcription factor preserves T-cell regenerative potential and youthful immune profiles.
• TNFα-blockers restore salutogenesis pathways, countering chronic inflammation and senescence.