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April 30 in Longevity and AI

Gathered globally: 10, selected: 10.

The News Aggregator is an artificial intelligence system that gathers and filters global news on longevity and artificial intelligence, and provides tailored multilingual content of varying sophistication to help users understand what's happening in the world of longevity and AI.


Researchers at the University of Kentucky and collaborators design MyoVision-US, a software leveraging DeepLabV3 with a ResNet50 backbone for semantic segmentation and post-processing to quantify quadriceps and tibialis anterior thickness, cross-sectional area, and echo intensity. The AI achieves excellent consistency (ICC >0.92) and reduces analysis time by 99.8%, aiding critical and chronic illness assessment.

Key points

  • DeepLabV3-ResNet50 models segment quadriceps complex and tibialis anterior ultrasound images.
  • Post-processing uses contour extraction, morphological opening/closing, and cubic spline smoothing to refine masks.
  • Software calculates muscle thickness, cross-sectional area, and echo intensity via pixel counts and grayscale averaging.
  • Validation shows Dice ~0.90, IoU ~0.88, and ICCs of 0.92–0.99 compared to manual analysis.
  • Automated pipeline analyzes 180 images in 247 s versus 24 h manually, saving 99.8% of analysis time.

Why it matters: Automating muscle ultrasound analysis transforms bedside assessments by delivering rapid, reproducible measurements that previously required expert manual effort. This scalability can improve monitoring of muscle wasting in critically ill and cancer patients, reduce human bias, and pave the way for real-time clinical integration.

Q&A

  • What is semantic segmentation?
  • How does echo intensity reflect muscle quality?
  • Why use Intraclass Correlation Coefficient (ICC)?
  • What roles do Dice coefficient and IoU play?
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Development of an artificial intelligence powered software for automated analysis of skeletal muscle ultrasonography

An aging research team applies miRNA enrichment analysis and an age-related genetic database to isolate a four-strand microRNA cocktail (E5) within stem-cell–derived extracellular vesicles. Delivered to senescent fibroblasts, E5 downregulates p16, p21 and inflammatory interleukins, outperforming native vesicles. In naturally aged mice, systemic E5 injections reduce senescence and DNA damage markers in liver tissue, highlighting a non-senolytic approach to cellular rejuvenation.

Key points

  • Four-miRNA cocktail (E5) derived from stem cell EVs modulates senescence.
  • Delivery via extracellular vesicles reduces SA-β-gal activity by ~30% in fibroblasts.
  • E5 downregulates p21, p16, IL-1β and IL-6 through PCAF and HIPK2 suppression.
  • In 24-month-old mice, systemic E5 dosing lowers senescence and DNA damage markers in liver tissue.
  • Non-senomorphic approach spares cell viability while targeting aging pathways.

Why it matters: This miRNA-loaded EV approach offers a non-senolytic alternative that reprograms aging cells without inducing cell death, potentially reducing side effects of current therapies. By targeting multiple senescence pathways, it could pave the way for precise, rejuvenative treatments in age-related diseases.

Q&A

  • What are extracellular vesicles?
  • How do microRNAs regulate cellular senescence?
  • Why combine four microRNAs into an E5 cocktail?
  • How was senescence measured in vitro and in vivo?
  • What role do PCAF and HIPK2 play in aging?
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How Extracellular Vesicles From Stem Cells Fight Senescence - Researchers have discovered a cocktail of micro-RNA strands that make some extracellular vesicles (EVs) effective in reducing cellular senescence and published their findings in Aging Cell.

A team led by Rabinowitz published in IJ STEM Ed demonstrates how embedding foundational machine learning modules within informal learning settings—such as after-school programs and science clubs—enables high school students to conduct ecological modeling and genetic data analysis, thereby enhancing computational thinking. The curriculum employs supervised and unsupervised learning exercises, scaffolding, and mentorship to incrementally develop students’ abilities to formulate hypotheses and interpret complex data.

Key points

  • Accessible programming modules introduce supervised and unsupervised machine learning tasks.
  • Informal settings like after-school clubs provide flexible, collaborative environments for data-driven science.
  • Curriculum addresses feature selection, overfitting, and evaluation metrics to build robust modeling skills.
  • Structured mentorship supports autonomy and growth mindset while preventing cognitive overload.
  • Mixed-method assessments show significant gains in students’ computational thinking, data literacy, and STEM interest.

Why it matters: Embedding machine learning into informal science education shifts the paradigm by democratizing access to computational skills and lowering classroom barriers. This scalable model fosters data literacy across diverse youth populations and equips the next generation with tools vital for addressing complex societal and scientific challenges.

Q&A

  • What is an informal learning setting?
  • How are supervised and unsupervised learning used in the curriculum?
  • What is computational thinking and why does it matter?
  • How do educators scaffold complex machine learning concepts?
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Effective Machine Learning Science Curriculum for Teens

A team from Nanjing Audit University investigates how Big Five personality traits influence static and dynamic trust in AI-driven drone missions across PC and VR modalities. Using a D3QN-based UAV simulation in Unity, they measure trust before and after interaction to inform adaptive, personality-aware human–machine interface designs.

Key points

  • Unity-based UAV surveillance simulation uses D3QN for autonomous path planning and obstacle avoidance.
  • Chinese TIPI questionnaire measures Big Five traits; extroversion and emotional stability highlighted.
  • Static trust (T0) assessed pre-interaction; dynamic trust (T1) measured post-interaction on PC and VR.
  • Extroversion significantly predicts initial trust; emotional stability enhances post-interaction trust in PC.
  • Static trust consistently predicts dynamic trust across modalities, explaining up to 21.9% of T1 variance.
  • VR yields higher initial trust, while PC delivers greater dynamic trust, per independent t-tests.

Why it matters: By revealing static trust as the foundation for evolving human-machine trust and identifying extroversion and emotional stability as key drivers, this study guides the design of adaptive, user-centric AI systems. Tailoring interfaces to individual personalities can enhance safety, reliability, and long-term engagement in AI applications.

Q&A

  • What distinguishes static and dynamic trust?
  • How does the D3QN algorithm function here?
  • Why compare PC and VR interaction?
  • Which personality traits matter most?
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Researchers at UT Health San Antonio define immune resilience as the capacity to balance inflammation and immune defense, stratifying over 17,000 participants into preservers, reconstituters, or degraders based on T-cell markers and TCF7 expression. Their analysis reveals a significant survival advantage linked to robust immune profiles.

Key points

  • Classified ~17,500 individuals into IR-preservers, reconstituters, and degraders using CD4/CD8 ratios
  • Identified SAS-1 and MAS-1 molecular signatures via transcriptomic and proteomic profiling
  • Demonstrated TCF7 transcription factor’s central role in maintaining T-cell multipotency and survival
  • Found up to 15-year survival advantage for high-resilience individuals aged 40–70
  • Highlighted midlife (40–70 years) as a critical intervention window for preserving immune resilience

Why it matters: This research reframes aging trajectories by positioning immune resilience as a modifiable determinant of longevity. By identifying TCF7 and molecular signatures linked to survival, it opens avenues for targeted interventions to preserve immune function and mitigate age-associated mortality risk.

Q&A

  • What is immune resilience?
  • How do IR-preservers, reconstituters, and degraders differ?
  • What role does TCF7 play in immune resilience?
  • How is immune resilience assessed in studies?
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Immune Resilience Is a Strong Determinant of Mortality - A new study defines the concept of immune resilience and positions it as a central determinant of aging trajectories, linking it to survival, inflammation control, and the body’s ability to withstand stress.

A coalition of AI security companies uses machine learning algorithms to analyze broker behaviors, transaction histories, and regulatory compliance, delivering real-time fraud alerts to investors worldwide through intuitive interfaces.

Key points

  • Dynamic AI tools analyze online brokers and investment platforms for fraud indicators
  • Real-time scanning of extensive financial data enables instantaneous scam alerts
  • Deep learning and anomaly detection uncover hidden fraud patterns beyond human scrutiny
  • User-generated reports enhance AI accuracy by feeding continuous feedback loops
  • Blockchain integration confirms transaction authenticity for an additional security layer
  • Customized alerts tailor warnings to individual investor profiles and risk preferences

Q&A

  • How does AI detect online scams?
  • What data does AI use for fraud analysis?
  • How is user privacy protected?
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How to Report Scam Using Artificial Intelligence to Improve Online Safety

Epidemiologists analyzing decades of cohort data identify consistent morning walking as a key longevity factor, demonstrating that 30–40 minutes of moderate activity enhances circadian alignment, insulin sensitivity, and telomere maintenance to reduce age-related disease risk.

Key points

  • Longitudinal studies link 4,000–8,000 daily steps to a 30–50% reduction in mortality risk.
  • Morning walking aligns circadian rhythms, enhances insulin sensitivity, and improves metabolic health.
  • Regular walking slows telomere shortening and increases BDNF release for cognitive preservation.
  • Cardiovascular benefits include lower resting heart rate, arterial elasticity, and improved lipid profiles.
  • Exposure to outdoor environments during walks reduces chronic inflammation via fresh air and greenery.
  • Habit formation strategies emphasize brief starts, cue–reward loops, and consistency over intensity.

Why it matters: This finding underscores a paradigm shift toward simple, accessible lifestyle interventions for lifespan extension. By demonstrating that moderate, routine movement can modulate key aging biomarkers and cardiovascular risk factors, it offers a cost-effective, widely adoptable strategy to improve population health outcomes.

Q&A

  • How does walking slow cellular aging?
  • Why are morning walks more beneficial?
  • What is the optimal walking duration and intensity?
  • Can starting a walking regimen later in life still help?
  • How do I build a sustainable walking habit?
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The morning habit linked to reaching your 90s

African governments adopt a phased plan that maps education systems, updates curricula, and establishes pilot AI Centers of Excellence, followed by mass teacher certification and digital hubs to build an AI-skilled workforce aligned with AfCFTA and Agenda 2063.

Key points

  • 2025: conduct national audits and establish National AI-Education Policies linked to AU Digital Transformation Strategy.
  • 2026: integrate AI modules into core curricula and launch pilot AI Centers of Excellence nationwide.
  • 2027: certify at least 10,000 teachers via hybrid AI teaching programs and deploy Online AI Literacy Hubs.
  • Mobilize $2.5 billion through national budgets, diaspora grants, multilateral loans, CSR, and Pan-African AI Education Fund.
  • Leverage AiAfrica Project’s modular training to fast-track AI literacy and ecosystem partnerships.

Why it matters: This strategic AI education roadmap equips Africa with the human capital and institutional frameworks needed to compete in the Fourth Industrial Revolution. By investing in teachers, infrastructure, and financing mechanisms now, the continent can avoid digital dependency, foster innovation ecosystems, and unlock sustainable economic growth.

Q&A

  • What is the AiAfrica Project?
  • Why is teacher training crucial for AI education?
  • What are AI Centers of Excellence?
  • How will Africa finance this AI roadmap?
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AI Education from Kindergarten to University: Global Trends, Lessons, and Strategic Roadmap for Africa

MarketsandMarkets’ latest forecast projects the vision transformers market to expand at a 34.2% CAGR, from USD 0.2 billion in 2023 to USD 1.2 billion by 2028. The integration of advanced AI and deep learning techniques enhances image segmentation, object detection, and captioning capabilities across verticals like healthcare & life sciences, automotive, and retail, with professional services driving significant adoption.

Key points

  • Market size grows from USD 0.2 billion in 2023 to USD 1.2 billion by 2028 at a 34.2% CAGR.
  • Offering segments include solutions and professional services, with services showing highest CAGR.
  • Applications span image segmentation, object detection, and captioning; captioning leads growth.
  • Verticals cover healthcare & life sciences, automotive ADAS, and retail visual search.
  • North America holds largest share due to major tech firms and advanced regulations.

Why it matters: The rapid expansion of the vision transformers market underscores a paradigm shift toward transformer-based computer vision in critical industries, promising more accurate and scalable image analysis. By leveraging self-supervised learning to reduce annotation needs, ViTs offer cost-effective deployment and enhanced cross-domain generalization, accelerating AI adoption in healthcare diagnostics, autonomous driving, and e-commerce.

Q&A

  • What distinguishes vision transformers from CNNs?
  • Why is self-supervised learning important for vision transformers?
  • How do professional services influence market growth?
  • What factors drive high growth in image captioning applications?
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Surreality, founded by Dewight Rutherford, integrates AI-driven Digital Essences, an immersive AR interface and blockchain-secured Echosphere to achieve digital immortality. Its platform synthesizes personal data into dynamic virtual companions that evolve posthumously, supports grief healing through nostalgia therapy and employs SurrealiCoin for decentralized governance. This innovative ecosystem preserves emotional continuity, enabling enduring intergenerational connections and secure legacy management beyond biological life.

Key points

  • Digital Essences: AI-driven avatars synthesized from voice, text, video and biometric data using deep learning and natural language processing.
  • Echosphere: a blockchain-secured, decentralized digital biosphere hosting adaptive Digital Essences across distributed renewable energy networks.
  • AR Glasses: proprietary augmented reality hardware offering holographic rendering and spatial audio to enable real-time interactions with emotional AI companions.
  • SurrealiCoin: native cryptocurrency for decentralized governance, resource allocation and incentive mechanisms within the platform.
  • Nostalgia Therapy: immersive VR experiences integrating multisensory cues and AI-curated therapeutic frameworks for grief support and memory reinforcement.
  • Smart Urns & Memorial Landscapes: interactive end-of-life services enabling holographic memorials and evolving digital environments within the Echosphere.

Q&A

  • What is a Digital Essence?
  • How does the Echosphere ensure data security?
  • What is SurrealiCoin used for?
  • What is Nostalgia Therapy?
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Surreality: Charting the Future of Digital Immortality and Emotional Continuity